Supplements
Management of Thrombosis in Polycythemia Vera: The Advanced Practitioner Perspective
This supplement to JADPRO explores two real-life cases of thrombosis in the setting of underlying polycythemia vera.
Guest Editor
Lindsey Lyle, MS, PA-C
University of Colorado Cancer Center
Lindsey E. Kalhagen, PA
Northwestern Medicine
Julie Huynh-Lu, PA
The University of Texas MD Anderson Cancer Center
Editorial
Managing Thrombosis in Polycythemia Vera: The Advanced Practitioner Perspective
Lindsey Lyle, MS, PA-C, Guest Editor
Grand Rounds
Budd-Chiari Syndrome as Initial Manifestation of Polycythemia Vera: Complexities in the Management of Younger Patients
Lindsey Lyle,(1) MS, PA-C, and Lindsey E. Kalhagen,(2) PA
Grand Rounds
Optimizing Treatment Strategies in Patients With Polycythemia Vera Who Develop a Thrombotic Event on Frontline Therapy
Lindsey Lyle,(1) MS, PA-C, and Julie Huynh-Lu,(2) PA
ASH Highlights and Commentary: The Advanced Practitioner Perspective
Selected abstracts from the 61th Annual Meeting of the American Society of Hematology
This supplement to JADPRO provides an overview of several abstracts that were presented at the 2019 ASH Annual Meeting, along with expert commentary that aims to contextualize the information presented at ASH for the advanced practitioner.
Guest Editor
Sandra E. Kurtin, PhD, ANP-C, AOCN®
The University of Arizona Cancer Center
Amy Pierre, ANP-BC
Memorial Sloan Kettering Cancer Center
Sara Tinsley, PhD, APRN, AOCN®
Moffitt Cancer Center and Research Institute
Editorial
The Advanced Practitioner’s Role in Treating Older Adults With Hematologic Malignancies
Sandra E. Kurtin, PhD, ANP-C, AOCN®
Meeting Abstract
ASH Highlights and Commentary: Chronic Lymphocytic Leukemia

Meeting Abstract
ASH Highlights and Commentary: Acute Myeloid Leukemia and Myelodysplastic Syndromes

Meeting Abstract
ASH Highlights and Commentary: Multiple Myeloma

Optimizing Treatment and Improving Outcomes for Patients With Acute Myeloid Leukemia: A Guide for Advanced Practitioners
A continuing education activity for nurse practitioners, PAs, clinical nurse specialists, advanced degree nurses, oncology and hematology nurses, pharmacists, and physicians.
This certified activity is supported by educational grants from Agios Pharmaceuticals, Inc. and Jazz Pharmaceuticals, Inc.
Editorial
Acute Myeloid Leukemia: An Ever-Changing Disease
Nancy M. Nix, PharmD, BCPS, BCOP, and Allyson Price, MPAS, PA-C
Review Article
Optimizing Use of Newly Approved Agents for Acute Myeloid Leukemia
Nancy M. Nix, PharmD, BCPS, BCOP, and Allyson Price, MPAS, PA-C
Review Article
The Role of the Advanced Practitioner in Enhancing Outcomes
Nancy M. Nix, PharmD, BCPS, BCOP, and Allyson Price, MPAS, PA-C
Appendix
Appendix: Key Information on Newly Approved AML Drugs
Nancy M. Nix, PharmD, BCPS, BCOP, and Allyson Price, MPAS, PA-C
CAR T-Cell Therapy for Large B-Cell Lymphoma
Practical information for the advanced practitioner on a revolutionary cancer treatment
This supplement to JADPRO, developed in partnership with Nexus Global Group Science LLC, aims to provide practical information to advanced practitioners on a number of considerations when implementing CAR T-cell therapy. It is sponsored by Kite, a Gilead Company.
Editorial
CAR T-Cell Therapy for Large B-Cell Lymphoma
Maritza C. Alencar, DNP, MBA, APRN-BC, BMTCN®
Review Article
Anti-CD19 CAR T-Cell Therapy for Adult Patients With Refractory Large B-Cell Lymphoma
Kathleen McDermott, RN, BSN, OCN®, BMTCN®, and Lauren Spendley, AGNP, MSN, AOCN®
Review Article
CAR T-Cell Therapy: Adverse Events and Management
Sherry Adkins, RN, MSN, ANP-C
Review Article
Educating Multidisciplinary Care Teams, Patients, and Caregivers on CAR T-Cell Therapy
Alix Beaupierre, RN, BSN, OCN®, Nicole Kahle, MS, RN, OCN®, BMTCN®, Rachel Lundberg, PA-C, MPAS, and Amy Patterson, MSN, APRN, AOCNS®, BMTCN®
ASH Highlights and Commentary:
The Advanced Practitioner Perspective
Selected abstracts from the 60th Annual Meeting of the American Society of Hematology
This supplement to JADPRO provides an overview of several abstracts that were presented at the 2018 ASH Annual Meeting, along with expert commentary that aims to contextualize the information presented at ASH for the advanced practitioner.
Guest Editor
Sandra E. Kurtin, PhD, ANP-C, AOCN®
The University of Arizona Cancer Center
Josh Epworth, ARNP
University of Washington
Lindsey Lyle, MS, PA-C
University of Colorado, Anschutz Medical Campus
Editorial
A Letter From the Guest Editor
Sandra E. Kurtin, PhD, ANP-C, AOCN®
Commentary
ASH Highlights and Commentary: Multiple Myeloma
Josh Epworth, ARNP
Commentary
ASH Highlights and Commentary: Acute Myeloid Leukemia
Lindsey Lyle, MS, PA-C
Commentary
ASH Highlights and Commentary: Leukemias and Lymphomas
Sandra E. Kurtin, PhD, ANP-C, AOCN®
Immuno-Oncology Therapy Essentials: Proactive Management of Immune-Related Adverse Events
This supplement, certified for CME/CE/CPE credit, is jointly provided by:
Editorial
Immuno-Oncology Essentials: An Overview
Brianna Hoffner, MSN, ANP-BC, AOCNP®
Review Article
Meeting the Challenge of Immune-Related Adverse Events With Optimized Telephone Triage and Dedicated Oncology Acute Care
Brianna Hoffner, MSN, ANP-BC, AOCNP®, and Krista M. Rubin, MS, FNP-BC
Review Article
PD-1/PD-L1 Inhibitors for Non–Small Cell Lung Cancer: Incorporating Care Step Pathways for Effective Side-Effect Management
Marianne J. Davies, DNP, MSN, RN, APRN, CNS-BC, ACNP-BC, AOCNP®
Review Article
Checkpoint Inhibitor Immunotherapy for Head and Neck Cancer: Incorporating Care Step Pathways for Effective Side-Effect Management
Casey Fazer, PA-C
Review Article
Immune-Related Adverse Events From Immunotherapy: Incorporating Care Step Pathways to Improve Management Across Tumor Types
Laura S. Wood, RN, MSN, OCN®
Appendix
Care Step Pathway Tools for Immune-Related Adverse Event Assessment and Management

Understanding the Role of Targets and Pathways in the Treatment of Melanoma
This CME/CE/CPE certified supplement is jointly provided by:
Editorial
A Letter From the Guest Editors
Lisa A. Kottschade, APRN, MSN, CNP, and LeAnn B. Norris, PharmD, FCCP, BCPS, BCOP
Editorial
A Brighter Future for Patients With Melanoma
Lisa A. Kottschade, APRN, MSN, CNP, and LeAnn B. Norris, PharmD, FCCP, BCPS, BCOP
Review Article
Diagnosis, Evaluation, and Surgical Management of Melanoma
Brianna Hoffner, MSN, ANP-BC, AOCNP®, and Christan G. Bartsch, MSHS, PA-C, MPH
Review Article
Harnessing the Immune System in the Treatment of Melanoma
Suzanne McGettigan, MSN, CRNP, AOCN®
Review Article
BRAF/MEK Inhibition in Melanoma: An Update
Lisa A. Kottschade, APRN, MSN, CNP, and Kathleen M. Madden, RN, MSN, FNP-BC, AOCNP®, APHN
Review Article
Mutations Beyond BRAF V600
Mollie Reed, MSN, ACNP-BC
Review Article
Melanomas of Noncutaneous Origin: Diagnosis, Treatment, and Outcomes
Lisa A. Kottschade, APRN, MSN, CNP
Review Article
Supportive Care and Management of Treatment-Related Adverse Effects From Immune Checkpoint Inhibitors and Targeted Therapies in Melanoma
Krista M. Rubin, MS, FNP-BC, and Lisa A. Kottschade, APRN, MSN, CNP
Review Article
Drug-Drug Interactions in Melanoma
LeAnn B. Norris, PharmD, FCCP, BCPS, BCOP
Appendix
Appendix
Compiled by Lisa A. Kottschade, APRN, MSN, CNP
Understanding the Role of Targets and Pathways in the Treatment of Chronic Lymphocytic Leukemia
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
This CME/CE/CPE accredited supplement is jointly provided by:
Faculty
Christopher Arp, PharmD, Levine Cancer Institute—Carolinas HealthCare System, Department of Pharmacy
Kristan Augustin, PharmD, BCOP, Barnes-Jewish Hospital, Department of Pharmacy
Hani M. Babiker, MD, University of Arizona College of Medicine, Translational Genomics Research Institute, and University of Arizona Cancer Center
Andrew Garcia, PharmD, The University of Arizona Cancer Center
Ashley E. Glode, PharmD, BCOP, Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences
Amy Goodrich, MSN, CRNP, Johns Hopkins School of Medicine and The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Alyssa Hinchman, PharmD, The University of Arizona Cancer Center
Lindsay Hladnik, PharmD, BCOP, Washington University in Saint Louis School of Medicine, Department of Medicine
Nadia Khan, MD, Fox Chase Cancer Center
Sandra E. Kurtin, PhDc, ANP-C, AOCN®, The University of Arizona Cancer Center
Ali McBride, PharmD, BCOP, The University of Arizona Cancer Center
Lisa Nodzon, PhD, ARNP, AOCNP®, Department of Malignant Hematology, Moffitt Cancer Center
Javier Pinilla-Ibarz, MD, PhD, Department of Malignant Hematology, Moffitt Cancer Center
Barbara Barnes Rogers, CRNP, MN, AOCN®, ANP-BC, Fox Chase Cancer Center
Nina Wagner-Johnston, MD, Johns Hopkins School of Medicine and The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
This activity is supported by unrestricted educational grants from
Gilead Sciences Inc. and Pharmacyclics LLC, an AbbVie Company and
Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC.
Editorial
A Letter From the Guest Editors
Sandra E. Kurtin, PhDc, ANP-C, AOCN®, and Ali McBride, PharmD, BCOP
Continuing Education
Chronic Lymphocytic Leukemia in 2018: What the Advanced Practitioner in Oncology Needs to Know
Sandra E. Kurtin, PhDc, ANP-C, AOCN®, and Ali McBride, PharmD, BCOP
Review Article
Scientific Advances in the Diagnosis and Risk Stratification of Chronic Lymphocytic Leukemia
Amy Goodrich, MSN, CRNP, and Nina Wagner-Johnston, MD
Review Article
Monoclonal Antibodies in Chronic Lymphocytic Leukemia
Lindsay Hladnik,(1) PharmD, BCOP, Kristan Augustin,(2) PharmD, BCOP, and Christopher Arp,(3) PharmD
Review Article
Small Molecules in Chronic Lymphocytic Leukemia: Novel Targets, New Challenges
Sandra E. Kurtin, PhDc, ANP-C, AOCN®, and Ali McBride, PharmD, BCOP
Review Article
Emerging Therapies in Chronic Lymphocytic Leukemia: Current Trials
Ashley E. Glode, PharmD, BCOP, and Hani M. Babiker, MD
Review Article
Risk-Adapted Treatment Strategies for Chronic Lymphocytic Leukemia
Lisa Nodzon, PhD, ARNP, AOCNP®, and Javier Pinilla-Ibarz, MD, PhD
Review Article
Supportive Care and Management of Treatment-Emergent Adverse Events in Chronic Lymphocytic Leukemia
Barbara Barnes Rogers, CRNP, MN, AOCN®, ANP-BC, and Nadia Khan, MD
Review Article
The Older Adult Living With Chronic Lymphocytic Leukemia: Implications for Oncology Providers, Patients, and Caregivers
Sandra E. Kurtin, PhDc, ANP-C, AOCN®
Appendix
Appendix
Compiled by Ali McBride, PharmD, BCOP, Andrew Garcia, PharmD, and Alyssa Hinchman, PharmD
The Role of the Advanced Practitioner in Maintaining Adherence in Patients on Oral Oncolytics
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
This CME/CE/CPE accredited supplement is jointly provided by:
Faculty
Diane Cope, PhD, ARNP-BC, AOCNP®, Florida Cancer Specialists and Research Institute
Kimberly M. Hicks, PharmD, MHA, HHCS Health Group of Companies
John Novak, CHA, PA-C, Rocky Mountain Cancer Centers and University of Colorado School of Medicine
Susan Scherer, RN, BSN, OCN®, RN Cancer Guides Solutions
This activity is supported by unrestricted educational grants from AstraZeneca; Bayer HealthCare Pharmaceuticals Inc.; Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; Novartis Pharmaceutical Corporation; and Taiho Oncology, Inc.
Editorial
A Letter From The Guest Editor

Review Article
The Role of the Advanced Practitioner in Maintaining Adherence in Patients on Oral Oncolytics
Kimberly M. Hicks,(1) PharmD, MHA, Diane Cope,(2) PhD, ARNP-BC, AOCNP®, John Novak,(3) CHA, PA-C, and Susan Scherer,(4) RN, BSN, OCN
The Emerging Role of Molecular Testing in Ovarian Cancer
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
This CME/CEU accredited supplement is jointly provided by:
Faculty
Courtney B. Cortez, NP, Indiana University Simon Cancer Center—IU Health
Cynthia L. Hunter, MS, LCGC, Indiana University Health
Patrick J. Kiel, PharmD, BCPS, BCOP, Indiana University School of Medicine, Indiana University Simon Cancer Center—IU Health
Jeanne M. Schilder, MD, Indiana University School of Medicine, Indiana University Simon Cancer Center—IU Health
This supplement is supported by an educational grant from AstraZeneca.
Editorial
The Rise of Genetic Testing in Managing Patients With Ovarian Cancer
Patrick J. Kiel, PharmD, BCPS, BCOP
Review Article
The Emerging Role of Molecular Testing in Ovarian Cancer
Patrick J. Kiel,(1) PharmD, BCPS, BCOP, Courtney B. Cortez,(2) NP, Cynthia L. Hunter,(3) MS, LCGC, and Jeanne M. Schilder,(1) MD
The Emerging Role of Molecular Testing in Non–Small Cell Lung Cancer
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
This CME/CEU accredited supplement is jointly provided by:
Faculty
Liang Cheng, MD, Indiana University School of Medicine
Gregory Durm, MD, Indiana University Simon Cancer Center—IU Health
Patrick J. Kiel, PharmD, BCPS, BCOP, Indiana University School of Medicine, Indiana University Simon Cancer Center—IU Health
Anna Livers-Ertel, ANP-BC, MSN, OCN®, Franciscan Health Cancer Center
This supplement is supported by an educational grant from AstraZeneca.
Editorial
The Rise of Genetic Testing in Managing Patients With Non–Small Cell Lung Cancer
Patrick J. Kiel, PharmD, BCPS, BCOP
Review Article
The Emerging Role of Molecular Testing in Non–Small Cell Lung Cancer
Patrick J. Kiel,(1),(2) PharmD, BCPS, BCOP, Liang Cheng,(1) MD, Anna Livers-Ertel,(3) ANP-BC, MSN, OCN®, and Gregory Durm,(2) MD
Genetic Counseling in Gynecologic Oncology: What Advanced Practitioners Need to Know
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
This CME/CEU accredited supplement is jointly provided by:
Faculty
Heather Hampel, MS, LGC
The Ohio State University Comprehensive Cancer Center
Brianna Hoffner, MSN, ANP-BC, AOCNP®
University of Colorado Cancer Center
Leigha Senter-Jamieson, MS, LGC
The Ohio State University Wexner Medical Center
Paula Anastasia, RN, MN, AOCN®
Cedars-Sinai Medical Center
This supplement is supported by an independent educational grant from AstraZeneca Pharmaceuticals LP
Editorial
Introduction
Heather Hampel, MS, LGC, Guest Editor
Review Article
Lynch Syndrome and Immunotherapy
Heather Hampel, MS, LGC, and Brianna Hoffner, MSN, ANP-BC, AOCNP®
Review Article
BRCA-Related Ovarian Cancers and the Role of PARP Inhibitor Therapy
Leigha Senter, MS, LGC, and Paula Anastasia, RN, MN, AOCN®
The Latest Advances in CAR T-Cell Therapy for Refractory and Relapsed Lymphomas and Leukemias
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
Faculty
Marco L. Davila, MD, PhD
Associate Member
Department of Blood and Marrow Transplantation
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida
This activity is supported by an educational grant from Kite Pharma, Inc.
Continuing Education
CAR T-Cell Therapy: An Approach Whose Time Has Come

Continuing Education
The Latest Advances in CAR T-Cell Therapy for Refractory and Relapsed Lymphomas and Leukemias
Marco L. Davila, MD, PhD
Understanding the Role of Targets and Pathways in the Treatment of Non–Small Cell Lung Cancer
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
A continuing education article for physicians, PAs, doctors of nursing practice, nurse practitioners, advanced practice nurses including clinical nurse specialists, and other advanced degree nurses.
Faculty
Lisa Cordes, PharmD, BCACP, BCOP, National Institutes of Health
Sandra Cuellar, PharmD, BCOP, University of Illinois Hospital and Health Sciences System—Pharmacy Practice
Marianne Davies, DNP, MSN, CNS, ACNP, AOCNP®, Yale University School of Nursing
Beth Eaby-Sandy, MSN, CRNP, OCN®, Abramson Cancer Center, Hospital of the University of Pennsylvania
Clell Hasenbank, PharmD, Providence St Mary Regional Cancer Center
Karen Oishi, MSN, APRN, AGPCNP-BC, OCN®, The University of Texas MD Anderson Cancer Center
Melinda Oliver, BA, BSN, RN, MPAP, The University of Texas MD Anderson Cancer Center
Samantha Schmidt, PharmD, Lexington Medical Center
Helen Shih, MSN, MPH, University of California, San Francisco Department of Thoracic Oncology
Grashma Vadakkel, PharmD(c), University of South Florida College of Pharmacy
Elizabeth S. Waxman, RN, MSN, AOCN®, ANP-BC, The University of Texas MD Anderson Cancer Center
This supplement is supported by educational grants from the following companies: Genentech and Merck Sharp & Dohme Corp.
Editorial
Letter From the Guest Editors

Editorial
Take a Deep Breath: More Treatment Options for Non–Small Cell Lung Cancer
Lisa Cordes, PharmD, BCACP, BCOP, and Elizabeth S. Waxman, RN, MSN, AOCN®, ANP-BC
Review Article
Diagnosis of Lung Cancer
Marianne Davies, DNP, MSN, CNS, ACNP, AOCNP®, and Helen Shih, MSN, MPH
Review Article
Fundamentals of Lung Cancer Staging
Marianne Davies, DNP, MSN, CNS, ACNP, AOCNP®
Review Article
Predictive and Prognostic Biomarkers and Related Therapies in Non–Small Cell Lung Cancer
Samantha Schmidt, PharmD, and Grashma Vadakkel, PharmD(c)
Review Article
Supportive Care and Management of Treatment-Emergent Adverse Events With Targeted Therapy in Non–Small Cell Lung Cancer
Clell Hasenbank, PharmD
Review Article
Emerging Biomarkers in Non–Small Cell Lung Cancer
Melinda Oliver, BA, BSN, RN, MPAP
Review Article
Immunotherapy Mechanisms of Action in Non–Small Cell Lung Cancer
Beth Eaby-Sandy, MSN, CRNP, OCN®
Review Article
Unleashing the Immune System With Checkpoint Inhibitors in Non–Small Cell Lung Cancer: Clinical Review of Adverse Events
Sandra Cuellar, PharmD, BCOP
Review Article
Emerging Therapies in Non–Small Cell Lung Cancer: Clinical Trials With Novel Agents
Karen Oishi, MSN, APRN, AGPCNP-BC, OCN®
Tools and Technology
Resources for Patients With Non–Small Cell Lung Cancer and Their Caregivers and Providers
Elizabeth S. Waxman, RN, MSN, AOCN®, ANP-BC
Appendix
Appendix
Lisa Cordes, PharmD, BCACP, BCOP
Editorial
Priming the Pump Task Force

Managing the Care of Patients With HER2-Positive Breast Cancer: A Collaborative Practice Model
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
A continuing education article for physicians, PAs, doctors of nursing practice, nurse practitioners, advanced practice nurses including clinical nurse specialists, and other advanced degree nurses.
Faculty
Angela DeMichele, MD, MSCE, Alan and Jill Miller Endowed Chair in Breast Cancer Excellence and Professor of Medicine and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
Jennie Greco Lattimer, MSN, BSN, CRNP, Oncology Nurse Practitioner, University of Pennsylvania Perelman Center for Advanced Medicine, Philadelphia, PA
This supplement is supported by an educational grant from Genentech.
Continuing Education
Continuing Education Information

Continuing Education
Meet the Team

Continuing Education
Managing the Care of Patients With HER2-Positive Breast Cancer: A Collaborative Practice Model
Angela DeMichele, MD, MSCE; Jennie Greco Lattimer, MSN, BSN, CRNP; and Rachel F.
Appendix
Appendix
Managing the Care of Patients With HER2-Positive Breast Cancer: A Collaborative Practice Model
The Advanced Practitioner's Guide to Multiple Myeloma
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
A continuing education activity for nurse practitioners, physician assistants, clinical nurse specialists, advanced degree nurses, oncology and hematology nurses, pharmacists, and physicians.
This CME/CE/CEU accredited supplement is jointly provided by
This supplement has been developed by members of the International Myeloma Foundation Nurse Leadership Board
Faculty
Page Bertolotti, RN, BSN, OCN, Samuel Oschin Cancer Center at Cedars-Sinai Medical Center
Kevin Brigle, PhD, NP, VCUHS Massey Cancer Center
Donna D. Catamero, ANP-BC, OCN, CCRC, Mount Sinai Medical Center
Kathleen Colson, RN, BSN, BS, Dana-Farber Cancer Center
Hollie Devine, MSN, ANP-BC, The Ohio State University Medical Center James Cancer Hospital
Deborah Doss, RN, OCN, Dana-Farber Cancer Center
Beth Faiman, PhD, MSN, APRN-BC, AOCN, Cleveland Clinic Taussig Cancer Institute
Elizabeth Finley-Oliver, RN, BSN, OCN, H. Lee Moffitt Cancer Center and Research Institute
Charise Gleason, MSN, NP-BC, AOCNP, Winship Cancer Institute of Emory University
Sandra Kurtin, RN, MSN, AOCN, ANP-C, The University of Arizona Cancer Center
Patricia A. Mangan, RN, MSN, APRN-BC, Abramson Cancer Center at the University of Pennsylvania
Ali McBride, PharmD, MS, BCPS, BCOP, The University of Arizona Cancer Center
Ann McNeill, RN, MSN, APN, John Theurer Cancer Center at HUMC
Teresa Miceli, RN, BSN, OCN, Mayo Clinic-Rochester
Kimberly Noonan, RN, ANP, AOCN, Dana-Farber Cancer Center
Tiffany Richards, MS, ANP, AOCNP, MD Anderson Cancer Center
Sandra Rome, RN, MN, AOCN, CNS, Cedars-Sinai Medical Center
Joseph Tariman, PhD, ANP-BC, DePaul University
Daniel Verina, BS, BSN, MSN, ACNP-BC, Mount Sinai Medical Center
This supplement is provided by independent educational grants from the following companies: Takeda Oncology, Celgene Corporation, Binding Site, and Adaptive Biotechnologies.
Continuing Education
Continuing Education Information

Editorial
The Future is Bright
Sandra Kurtin, RN, MSN, AOCN®, ANP-C
Editorial
The Continuum of Care in Multiple Myeloma Redefined: Challenges and Opportunities
Sandra Kurtin, RN, MSN, AOCN®, ANP-C, Guest Editor
Review Article
Sequencing of Treatment and Integration of Clinical Trials
Beth Faiman,(1) PhD, MSN, APRN-BC, AOCN®, Charise Gleason,(2) MSN, NP-BC, AOCNP®, Kathleen Colson,(3) RN, BSN, BS, Ann McNeill,(4) RN, MSN, APN, and Donna Catamero,(5) ANP-BC, OCN®, CCRC, on behalf of the International Myeloma Foundation Nurse Leadership Board
Review Article
Palliative Care in Multiple Myeloma
Tiffany Richards,(1) MS, ANP, AOCNP®, and Kevin Brigle,(2) PhD, NP, on behalf of the International Myeloma Foundation Nurse Leadership Board
Prescriber's Corner
New Agents in the Treatment of Multiple Myeloma
Beth Faiman,(1) PhD, MSN, APRN-BC, AOCN®, Ali McBride,(2) PharmD, MS, BCPS, BCOP, Hollie Devine,(3) MSN, ANP-BC, Charise Gleason,(4) MSN, NP-BC, AOCNP®, and Sandra Kurtin,(5) RN, MSN, AOCN®, ANP-C, on behalf of the International Myeloma Foundation Nurse Leadership Board
Prescriber's Corner
Monoclonal Antibodies in the Treatment of Multiple Myeloma
Charise Gleason,(1) MSN, NP-BC, AOCNP®, Hollie Devine,(2) MSN, ANP-BC, Beth Faiman,(3) PhD, MSN, APRN-BC, AOCN®, Deborah Doss,(4) RN, OCN®, and Sandra Kurtin,(5) RN, MSN, AOCN®, ANP-C, on behalf of the International Myeloma Foundation Nurse Leadership Board
Grand Rounds
Updates in the Diagnosis and Monitoring of Multiple Myeloma
Sandra Kurtin,(1) RN, MSN, AOCN®, ANP-C, Page Bertolotti,(2) RN, BSN, OCN®, Kevin Brigle,(3) PhD, NP, and Daniel Verina,(4) BS, BSN, MSN, ACNP-BC, on behalf of the International Myeloma Foundation Nurse Leadership Board
Practice Matters
Adherence, Persistence, and Treatment Fatigue in Multiple Myeloma
Sandra Kurtin,(1) RN, MSN, AOCN®, ANP-C, Kathleen Colson,(2) RN, BSN, BS, Joseph Tariman,(3) PhD, ANP-BC, Beth Faiman,(4) PhD, MSN, APRN-BC, AOCN®, and Elizabeth Finley-Oliver,(5) RN, BSN, OCN, on behalf of the International Myeloma Foundation Nurse Leadership Board
Tools and Technology
Resources for Patients and Caregivers With Multiple Myeloma and Their Providers
Kevin Brigle, PhD, NP, on behalf of The International Myeloma Foundation Nurse Leadership Board
Appendix
Multiple Myeloma Treatment Options for Newly Diagnosed, Relapsed, and Refractory Disease
Kimberly Noonan,(1) RN, ANP, AOCN®, Teresa S. Miceli,(2) RN, BSN, OCN®, Patricia Mangan,(3) RN, MSN, APRN-BC, and Sandra Rome,(4) RN, MN, AOCN®, CNS, on behalf of the International Myeloma Foundation Nurse Leadership Board
Methotrexate and Fluorouracil Toxicities:
What Advanced Practitioners in Oncology Need to Know
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
Faculty
Christopher J. Campen, PharmD, BCPS, BCOP, Arizona Cancer Center, University of Arizona
Wendy H. Vogel, MSN, FNP, AOCNP®, Wellmont Cancer Institute
Julie M. Vose, MD, MBA, University of Nebraska Medical Center
Continuing education credit is provided through the Meniscus Educational Institute, a triple accredited provider for CME/CE/CEU credits and contact hours, upon successful completion of the supplement and evaluation.
This activity is supported by an unrestricted educational grant from BTG International.
Continuing Education
Continuing Education Information

Meeting Report
Meet The Panel

Meeting Abstract
Methotrexate and Fluorouracil Toxicities: What Advanced Practitioners in Oncology Need to Know

Meeting Abstract
Case Studies: Collaborative Practice In Action

Meeting Abstract
Questions Answered About Glucarpidase

Meeting Abstract
Questions Answered About Uridine Triacetate

Collaborative Practice Enhances Supportive Care in Cancer: Chemotherapy-Induced Nausea and Vomiting
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
Faculty
Rita Wickham, PhD, RN, AOCN®, Rush University College of Nursing (Adjunct Faculty)
Sally Barbour, PharmD, BCOP, CPP, Duke University Medical Center
Teresa Scardino, RPA-C, MPAS, Memorial Sloan Kettering Cancer Center
Continuing education credit is provided through the Meniscus Educational Institute, a triple accredited provider for CME/CE/CEU credits and contact hours, upon successful completion of the supplement and evaluation.
Supported by an unrestricted educational grant from Heron Therapeutics (formerly AP Pharma)
Continuing Education
Continuing Education Information

Editorial
Collaborative Practice Enhances Supportive Care in Cancer: Chemotherapy-Induced Nausea and Vomiting
Rita Wickham, PhD, RN, AOCN® Sally Barbour, PharmD, BCOP, CPP Teresa Scardino, RPA-C, MPAS
Review Article
Risks for Chemotherapy-Induced Nausea and Vomiting: Capturing Relevant Data
Teresa Scardino, RPA-C, MPAS
Review Article
Actualizing Standards of Care for Chemotherapy-Induced Nausea and Vomiting
Sally Barbour, PharmD, BCOP, CPP
Review Article
Managing Chemotherapy-Induced Nausea and Vomiting: Past, Present, and Future
Rita Wickham, PhD, RN, AOCN®
Grand Rounds
Managing Chemotherapy-Induced Nausea and Vomiting: An Adaptable, Collaborative Approach for a Patient With Colon Cancer
Rita Wickham, PhD, RN, AOCN®, Sally Barbour, PharmD, BCOP, CPP, and Teresa Scardino, RPA-C, MPAS
Nursing Perspectives on Carfilzomib in Patients With Relapsed or Refractory Multiple Myeloma
Guest Editor
Sandra E. Kurtin, RN, MS, AOCN®, ANP-C
The supplement and associated publication costs were funded by Onyx Pharmaceuticals, Inc. Fishawack Communications, Inc., provided medical writing and editorial assistance, supported by Onyx Pharmaceuticals.
Review Article
Relapsed or Relapsed/Refractory Multiple Myeloma
Sandra E. Kurtin, RN, MS, AOCN®, ANP-C
Prescriber's Corner
Carfilzomib
J. Michael Vozniak, PharmD, BCOP
Review Article
The Side Effect Profile of Carfilzomib: From Clinical Trials to Clinical Practice
Laura McBride, RN, BSN, OCN®, CCRP, and Christine O. Samuel, RN, BSN, OCN®, CCRP
Grand Rounds
Treatment of Patients With Multiple Myeloma: A Relapsed and Refractory Case Study
Sandra E. Kurtin, RN, MS, AOCN®, ANP-C
Review Article
Treatment With Carfilzomib: A Promising Future for Multiple Myeloma
Donna Catamero, ANP-BC, OCN®, CCRC, and Charise Gleason, MSN, ANP, AOCNP®
Monitoring, Treatment Resistance, and Treatment Failure in Chronic Myeloid Leukemia
Breaking Barriers to Improved Outcomes
Jorge Eduardo Cortes, MD
The University of Texas MD Anderson Cancer Center
Houston, Texas
John M. Goldman, DM, FRCP, FRCPath, FMedSci
Imperial College
London, United Kingdom
Timothy P. Hughes, MD, MBBS
Centre for Cancer Biology
Adelaide, Australia
Faculty Perspectives by:
Patricia S. Ault, RN, FNP, and Mary Beth Rios, CCRP, RN
The University of Texas MD Anderson Cancer Center
Houston, Texas
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
CNE provided by MediCom Worldwide, Inc.
This activity is supported by an unrestricted educational grant from ARIAD Pharmaceuticals, Inc.
Continuing Education
Continuing Education Information

Review Article
Monitoring, Treatment Resistance, and Treatment Failure in CML: Breaking Barriers to Improved Outcomes
Jorge Eduardo Cortes, MD(1). John M. Goldman, DM, FRCP, FRCPath, FMedSci(2), and Timothy P. Hughes, MD, MBBS(3); Faculty Perspectives by Patricia S. Ault, RN, FNP(1), and Mary Beth Rios, CCRP, RN(1)
Proceedings of selected presentations from
2nd Annual Managing Hematologic Malignancies: The Balancing Act
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
Sandra Kurtin, RN, MS, AOCN®, ANP-C, University of Arizona and Arizona Cancer Center
Jean A. Ridgeway, MSN, APN, NP-C, AOCN®, University of Chicago Medical Center
Amy Goodrich, MSN, CRNP, John Hopkins Kimmel Cancer Center
Elizabeth Bilotti, MSN, RN, APN, OCN®, John Theurer Cancer Center, Hackensack University Medical Center
This activity is designed for oncology NPs, PAs, and CNSs interested in learning more about hematologic malignancies and the management of these patients.
This activity is jointly sponsored by Medical Education Resources, Inc., and Avid Education Partners, LLC.:
Supported by educational grants from Celgene, Cephalon Oncology, and Millennium: The Takeda Oncology Company.
Continuing Education
Continuing Education Information

Editorial
Managing Hematologic Malignancies: The Balancing Act
Sandra Kurtin, RN, MS, AOCN®, ANP-C
Review Article
Current Approaches to the Diagnosis and Management of Myelodysplastic Syndromes
Sandra Kurtin, RN, MS, AOCN®, ANP-C
Review Article
Risk Stratification and Management of Acute Myeloid Leukemia
Jean A. Ridgeway, MSN, APN, NP-C, AOCN®
Review Article
Update on the Management of Follicular Lymphomas
Amy Goodrich, MSN, CRNP
Review Article
Management of Multiple Myeloma and Serious Side Effects
Elizabeth Bilotti, MSN, RN, APN, OCN®
Oral Mucositis: Addressing the Causes, Challenges, and Clinical Management
Although this activity has expired, you may still view the supplement content. However, you will not be able to obtain CE credit.
Carrie F. Daly, MS, RN, AOCN®, Rush University Medical Center
Annette M. Quinn, MSN, RN, University of Pittsburgh Medical Center
Oral mucositis remains one of the most painful and debilitating side effects of cancer therapy. A working knowledge of the risk factors for oral mucositis and oral cavity assessment protocols is essential to early identification of signs and symptoms in high-risk patients. The use of evidence-based guidelines and patient education will facilitate symptom management and supportive care strategies designed to avoid reductions, delays, or discontinuation of cancer treatment.
CE provided by:
Continuing Education
Continuing Education Information

Review Article
Oral Mucositis: Addressing the Causes, Challenges, and Clinical Management
Carrie F. Daly, MS, RN, AOCN®, and Annette M. Quinn, MSN, RN