Continuing Education

Continuing Education Information

© 2016 Harborside Press®



Managing the Care of Patients With HER2-Positive Breast Cancer: A Collaborative Practice Model

A continuing education article for physicians, PAs, doctors of nursing practice, nurse practitioners, advanced practice nurses including clinical nurse specialists, and other advanced degree nurses.

Release date: November 17, 2016

Expiration date: November 17, 2017

Estimated time to complete this activity: 0.75 hour

Meniscus Educational Institute
3131 Princeton Pike, Building 1, Suite 205A
Lawrenceville, NJ 08648
Voice: 609-246-5000
Fax: 609-449-7969

Journal of the Advanced Practitioner in Oncology
94 North Woodhull Road
Huntington, NY 11743
Voice: 631-692-0800
Fax: 631-692-0805

© 2016, Meniscus Educational Institute. All rights reserved.

This supplement is supported by an educational grant from Genentech.



Angela DeMichele, MD, MSCE, Alan and Jill Miller Endowed Chair in Breast Cancer Excellence and Professor of Medicine and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

Jennie Greco Lattimer, MSN, BSN, CRNP, Oncology Nurse Practitioner, University of Pennsylvania Perelman Center for Advanced Medicine, Philadelphia, PA

Activity Rationale and Purpose

Providers use many frequently prescribed drugs across disease states without a clear understanding of their mechanisms: which targets they hit, what processes they alter, which of these actions are the key to therapeutic efficacy, and which are responsible for toxicity. Breast cancer expert faculty identified a lack of understanding of HER2 testing that is now standard practice for women with breast cancer, although it is not always clear which test to use and how test results impact selection of therapy.

Neoadjuvant therapy for patients with HER2-positive breast cancer can enhance resectability and reduce tumor burden prior to surgery and/or radiation therapy and may enhance outcomes.

Oncology nurses and other advanced practitioners need to understand the potential benefits of neoadjuvant therapy for HER2-positive breast cancer, the scientific basis for new HER2-targeted treatments that could improve neoadjuvant responses and/or tumor resectability, and in many cases educate patients and support them in the decision process.

Intended Audience

The activity’s target audience will consist of physicians, PAs, doctors of nursing practice, nurse practitioners, advanced practice nurses including clinical nurse specialists, and other advanced degree nurses.

Learning Objectives

After completing this educational activity, participants should be able to:

Describe scientific updates and key practice changes in the management of locally advanced and metastatic HER2-positive breast cancer

Review HER2 testing guidelines for patients with breast cancer

Discuss best sequencing of FDA approved targeted agents, mechanism of action and toxicities

Explain the role of neoadjuvant chemotherapy in HER2-positive breast cancer, including use of HER2-targeted agents

Describe collaboration between various members of the healthcare team (including but not limited to physician, nurse practitioner, PA, and pharmacist) in management strategies for patients with locally advanced and metastatic HER2-positive breast cancer

Continuing Education

Statement of Credit—Participants who successfully complete this activity (including the submission of the post-test and evaluation form) will receive a statement of credit.

CE Physician Logo

Physicians. This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Meniscus Educational Institute and the Advanced Practitioner Society for Hematology and Oncology (APSHO). The Meniscus Educational Institute is accredited by the ACCME to provide continuing medical education for physicians.

The Meniscus Educational Institute designates this journal article for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CE Nurse Logo

Nurses. This activity for 0.75 contact hour is provided by the Meniscus Educational Institute.

The Meniscus Educational Institute is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Provider approved by the California Board of Registered Nursing, Provider No. 13164, for 0.75 contact hour.

Financial Disclosures

All individuals in positions to control the content of this program (eg, planners, faculty, content reviewers) are expected to disclose all financial relationships with commercial interests that may have a direct bearing on the subject matter of this continuing education activity. Meniscus Educational Institute has identified and resolved all conflicts of interest in accordance with the MEI policies and procedures. Participants have the responsibility to assess the impact (if any) of the disclosed information on the educational value of the activity.



Angela DeMichele, MD, MSCE,
has served as a consultant for Novartis and Pfizer, and has received grants from Calithera Biosciences, Genentech, Novartis, and Pfizer.

Jennie Greco Lattimer, MSN, BSN, CRNP, has served on a speakers
bureau for Genentech.

Lead Nurse Planner

Wendy J. Smith, ACNP, AOCN®,
has nothing to disclose.


Alana Brody has nothing to disclose.

Chris Cherry has nothing to disclose.

Jeannine Coronna has nothing to disclose.

Claudine Kiffer has nothing to disclose.


Patti McLafferty has nothing to disclose.

Lynn Rubin has nothing to disclose.

Christine Wilson has nothing to disclose.

Annie Yueh has nothing to disclose.

Content Reviewers

Karen Abbas, MS, RN, AOCN®, has nothing to disclose.

Moshe Ornstein, MD, MA, has nothing to disclose.


This activity has been designed to provide continuing education that is focused on specific objectives. In selecting educational activities, clinicians should pay special attention to the relevance of those objectives and the application to their particular needs. The intent of all Meniscus Educational Institute educational opportunities is to provide learning that will improve patient care. Clinicians are encouraged to reflect on this activity and its applicability to their own patient population.

The opinions expressed in this activity are those of the faculty and reviewers and do not represent an endorsement by Meniscus Educational Institute of any specific therapeutics or approaches to diagnosis or patient management.

Product Disclosure

This educational activity may contain discussion of published as well as investigational uses of agents that are not approved by the US Food and Drug Administration. For additional information about approved uses, including approved indications, contraindications, and warnings, please refer to the prescribing information for each product.

How to Earn Credit

To access the learning assessment and evaluation form online, visit

Statement of Credit: Participants who successfully complete this activity (including scoring a minimum of 70% on the learning assessment and completing and submitting the evaluation form with an E-mail address) will be able to download a statement of credit.

Copyright © 2010-2022 Harborside Press, LLC All rights reserved.               
Home | Current Issue | Previous Issue | Submissions | About JADPRO | Advertising | Privacy Policy | Contact | Copyright Notice/Disclaimer | Subscribe
Bot trap - Don't go here
By continuing to browse this site you permit us and our partners to place identification cookies on your browser and agree to our use of cookies to identify you for marketing. Read our Privacy Policy to learn more.