Current Issue

VOL 11 NO 1 • JAN/FEB 2020

This issue’s cover illustration depicts pancreatitis by general diffuse redness and irritation. Close-up shows pancreatic acini, activation of digestive enzymes, and infiltration of white blood cells. Artwork by Alexandra Webber Baker © 2020, DNA Illustrations, Inc., Asheville, North Carolina.


Breast Density and Breast Cancer

Pamela Hallquist Viale, RN, MS, CNS, ANP

If a woman receives a screening mammogram that demonstrates high breast density, it is mandated that the mammogram report include a summary about how dense breast tissue is a common occurrence and that the density can make it harder to evaluate the results of the mammogram exam (American Cancer S...

Research & Scholarship

Implementation of Survivorship Care Plans in Patients With Glioblastoma

Casey B. Brown,(1) DNP, RN, AGPCNP-BC, Deborah Allen,(1) PhD, RN, CNS, FNP-BC, AOCNP®, Christina Cone,(1) DNP, APRN, ANP-BC, AOCNP®, and Susan M. Schneider,(2) PhD, RN, AOCN®, ACNS-BC, FAAN

Glioblastoma is often defined as a terminal diagnosis. Although this is sometimes inevitable, patients are living longer due to advances in therapy and symptom management (National Cancer Institute [NCI], 2013). Patients often go back to work and return to normal activities. Many report that they...

Grand Rounds

Management of Acute Pancreatitis Associated With Checkpoint Inhibitors

Barbara Barnes Rogers, CRNP, MN, AOCN®, ANP-BC, Terri Cuddahy, RN, MSN, OCN®, and Carolyn Zawislak, MPAS, PA-C

Case Study KG is a 55-year-old male who was diagnosed with stage IIIB squamous cell lung cancer (non–small cell lung cancer) in 2017. His medical history includes hypertension, diabetes, and hyperlipidemia, all of which have been under control for the past 5 years through medication. His type 2 ...

Continuing Education

CE Information: Advances in Oral Oncolytic Agents for Breast Cancer and Recommendations for Promoting Adherence

Advances in Oral Oncolytic Agents for Breast Cancer and Recommendations for Promoting Adherence Read the certified article Provided by Release date: 1/22/2020 Expiration date: 1/21/2021 Estimated time of completion: 1.0 hour Media: Certified journal article TARGET AUDIENCE This activi...

Continuing Education

Advances in Oral Oncolytic Agents for Breast Cancer and Recommendations for Promoting Adherence

Theresa Wicklin Gillespie, RN, MA, PhD, FAAN

Breast cancer represents the most common cancer among women in the United States and worldwide. The aging of the “baby boom” generation has contributed to an increase in breast cancer cases, since increasing age is a primary risk factor for breast cancer diagnosis (National Comprehensive Cancer N...

Grand Rounds

Dihydropyrimidine Dehydrogenase Deficiency: To Screen or Not to Screen?

Wendy H. Vogel,(1) MSN, FNP, AOCNP®, Ahmed Minhas,(2) MD, and Steven Baumrucker,(1) MD

Case Study SJ is a 69-year-old female with recurrent breast cancer. She was originally diagnosed with clinical stage IIIB, human epidermal growth factor receptor 2 (HER2)-positive infiltrating ductal carcinoma of the breast. She receives neoadjuvant chemotherapy with docetaxel, pertuzumab, and t...

Practice Matters

Metabolic Syndrome, Exercise, and Cardiovascular Fitness in Breast Cancer Survivors

M. Tish Knobf, PhD, RN, AOCN®, FAAN, and Sangchoon Jeon, PhD

The role of the advanced practitioner in oncology is to provide high-quality, patient-centered care to complex patients with unique needs (Ewing, 2015; Wall & Rawson, 2016). One aspect of oncology care is the challenge of managing cancer survivors who are at risk for or have comorbid illness ...

Prescriber's Corner

Gilteritinib: A Novel FLT3 Inhibitor for Relapsed/Refractory Acute Myeloid Leukemia

Dennis Marjoncu,(1) PharmD, BCOP, and Benjamin Andrick,(2) PharmD, BCOP

Acute myeloid leukemia (AML) is the most common adult leukemia, with an estimated incidence of 21,450 patients in 2019. Additionally, mortality remains high, with an estimated 10,920 deaths occurring in 2019 (American Cancer Society, 2019). The underlying pathophysiology is driven by clonal proli...

Diagnostic Snapshot

Management of Gastric Outlet Obstruction in a Patient With Gastric Cancer

Irene Thomas Thayil, PA-C

History Ms. H is a 72-year-old female with a personal history of CVA and PVD who presented with nausea, decreased appetite, and weight loss. She underwent an endoscopy that revealed a large, infiltrative, partially circumferential mass in the gastric curvature and prepyloric region of the stomach...

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