Hereditary Aspects of Colorectal Cancer: Mismatch Repair Genes Drive Lynch Syndrome
Presented by Heather Hampel,(1) MS, LGC, and Michael J. Hall,(2) MD, MS
1)The Ohio State University, Columbus, Ohio; 2)Fox Chase Cancer Center, Philadelphia, Pennsylvania
Presenters’ disclosures of conflicts of interest are found at the end of this article.
J Adv Pract Oncol 2018;9(3):311–315 |
© 2018 Harborside™
Lynch syndrome is the most common inherited form of colorectal cancer, affecting approximately 1 in 279 individuals, or 1.2 million people in the United States. It's also associated with a predisposition to endometrial, ovarian, and stomach cancers, among others. Advanced practitioners should be familiar with the genetics for this syndrome, as well as guidelines for screening and managing this common hereditary predisposition.
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