Grand Rounds

Optimizing the Management of Carcinoid Syndrome to Reduce the Impact of Diarrhea

Rory Randall,(1) CNP, AOCNP®, Bonita Bennett,(2) RN, BSN, Tiffany Valone,(3) PA-C, MS, OT, and Kirsten Blue,(3) PA-C, MS

(1) University Hospitals Seidman Cancer Center, Cleveland, Ohio; (2) University of Pennsylvania Health System, Philadelphia, Pennsylvania; (3) Moffitt Cancer Center, Tampa, Florida

Authors’ disclosures of conflicts of interest are found at the end of this article.

Kirsten Blue, PA-C, MS, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612. E-mail: kirsten.blue@moffitt.org


J Adv Pract Oncol 2019;10(8):862–872 | https://doi.org/10.6004/jadpro.2019.10.8.7 | © 2019 Harborside™


  

ABSTRACT

Diarrhea is often a presenting symptom in patients with neuroendocrine tumors (NETs). Frequently diagnosed in advanced stages, carcinoid syndrome diarrhea negatively impacts patients’ well-being and quality of life. This article will review the diagnostic work-up for neuroendocrine tumors and etiology and management of NET-related carcinoid syndrome diarrhea and provide guidance for advanced practitioners, including nurse practitioners, physician assistants, pharmacists, and dieticians, focusing on their role in patient and caregiver education regarding disease, symptom monitoring and management, development of patient-specific treatment, and survivorship plans.




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