3q26.2/EVI1 Rearrangement is Associated With Poor Prognosis in Classical Philadelphia Chromosome-Negative Myeloproliferative Neoplasms

The researchers from this recent study concluded that 3q26.2 rearrangement in classical Philadelphia chromosome-negative myeloproliferative neoplasms is associated with other concurrent cytogenetic abnormalities, a rapid disease progression and blast transformation, a poor response to chemotherapy, and a dismal prognosis.

 Modern Pathology