Targeted Next-Generation Sequencing Identified Novel Mutations in Triple-Negative Myeloproliferative Neoplasms

Mutations in JAK2, MPL and CALR genes have been identified in the majority of patients with myeloproliferative neoplasms (MPNs), and patients negative for these three mutations are the so-called triple-negative (TN) MPNs. In this study, the researchers found that both somatic and germline mutations may be detected in TN MPN patients.

 Med Oncol

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