Novel Hematological Parameters for the Evaluation of Patients With Myeloproliferative Neoplasms: the Immature Platelet and Reticulocyte Fractions

New automated hematology analyzers have led to the availability of novel hematological parameters, including the immature platelet fraction (IPF) and the immature reticulocyte fraction (IRF), both of potential interest in patients with myeloproliferative neoplasms (MPNs). In this study, researchers found that factors associated with high IRF among patients with polycythemia vera or essential thrombocythemia were low hemoglobin, high reticulocyte count, and a diagnosis of polycythemia vera. Among patients with myelofibrosis, the associated factors were peripheral blasts and elevated reticulocytes.  

 Ann Hematol

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