Diagnostic Snapshot

Indeterminate Thyroid Nodules: When to Worry?

Amanda Tibbels, MPAS, PA-C

From The University of Texas MD Anderson Cancer Center, Houston, Texas

Author’s disclosure of conflict of interest is found at the end of this article.

Correspondence to: Amanda Tibbels, MPAS, PA-C, 1400 Pressler Street, Houston, TX 77030. E-mail: amtibbels@mdanderson.org


J Adv Pract Oncol 2023;14(1):88–92 | https://doi.org/10.6004/jadpro.2023.14.1.9 | © 2023 Harborside™


  

ABSTRACT

Indeterminate thyroid nodules can present a confounding scenario for both provider and patient. Once a diagnosis of an indeterminate thyroid nodule is made, appropriate management can range from conservative observation to surgical resection. A thorough evaluation, including a dedicated history and physical examination, biochemical profile, pathologic information from a seasoned pathologist, and thyroid ultrasound by an experienced radiologist can help point health-care providers in the right direction. However, the ultimate diagnosis cannot be rendered unless surgical excision is performed. Provider and patient must agree on a personalized risk vs. benefit profile for the indeterminate thyroid nodule. 




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