Characteristics and Clinical Significance of Cytogenetic Abnormalities in Polycythemia Vera

Up to 20% of patients with polycythemia vera have karyotypic abnormalities at the time of initial diagnosis. Therefore, in this study the researchers aimed to address the significance of these cytogenetic abnormalities. They concluded that cytogenetic changes in polycythemia vera vary in different phases of disease and carry different prognostic impacts.