Young women who carry the BRCA1 and/or BRCA2 mutation and develop breast cancer seem to have similar survival compared with young women who have BRCA-negative breast cancer. However, women with BRCA-positive triple-negative breast cancer have an 11% survival advantage compared with those with BRCA-negative breast cancer, according to the results of a study presented at the 2016 San Antonio Breast Cancer Symposium. The study showed that patients with BRCA-positive breast cancer may safely delay bilateral mastectomy, since an immediate bilateral mastectomy within the first year of diagnosis did not affect survival.
The ASCO Post