MicroRNA-224 Inhibits Proliferation and Migration of Breast Cancer Cells by Down-Regulating Fizzled 5 Expression

Induction of frizzled 5 over-expression mitigated the miR-224-mediated inhibition of breast cancer cell proliferation. Collectively, these data indicated that miR-224 down-regulated the Wnt/β-catenin signaling possibly by binding to frizzled 5 and inhibited proliferation and migration of breast cancer cells.